When he was in his 20s he began having testosterone injections, giving him facial hair, a lower voice and altering his sexual organs.The couple met shortly after Beatie began taking the testosterone injection.
But at the age of 28 she had a hysterectomy because of severe endometriosis - where cells from the lining of the womb are found elsewhere in the body - so she couldn’t have any more children. The couple married in Hawaii in 2003.
Thomas had already had a mastectomy to remove his breasts, and hormone treatment that gave him an outwardly male appearance.
But he chose to keep his female sexual organs so the couple could have children.
They bought sperm from an anonymous donor and Beatie underwent artificial insemination. He eventually fell pregnant with Susan in late 2007 and had his next two children in quickly after, as he only had a short window of not taking testosterone.
He posed for a famous picture in 2007 which displayed him as heavily pregnant but with facial hair.
He told Oprah on her show four years ago: 'I wanted to have a child one day. I didn't know how. It was just a dream.'
In an interview in March, Beatie and Nancy explained the stresses and strains they faced on a daily basis since coming into the public eye.
Mr Beatie, 34, was born a woman - Tracey Lagondino - but had his breasts surgically removed and began taking males hormones several years ago. in short he is a woman in organ but he is a man physically thats the real story..